Atropine Sulphate Injection 1 ml
 
MANUFACTURER/ MARKETER
Vulcan Laboratories Pvt Ltd.
 
SALT COMPOSITION
Atropine Sulphate 0.65mg/ml Injection I.P.
 
 
PRODUCT INTRODUCTION
Atropine Sulphate Injection 1 ml belongs to a class of drugs known as 'anticholinergics', used to treat bradycardia (decreased heart rate). It restores normal heartbeat during cardiac arrest. It is also used to reduce saliva, mucus, or other secretions in the respiratory tract during surgery. It is further used as an antidote to treat organophosphate insecticide, nerve gas or mushroom poisonings.
Atropine Sulphate Injection 1 ml contains Atropine, which belongs to the class of muscarinic antagonists or parasympatholytics. It works by blocking the activity of acetylcholine (chemical messenger). As a result, this helps to bring back the blood pressure within the normal range and relaxes the heart. Hence, it treats symptomatic bradycardia and prevents sudden fall in blood pressure.
Atropine Sulphate Injection 1 ml may cause some common side effects like constipation, bloating, stomach pain, nausea, vomiting, dry eyes, blurred vision, dry mouth, fast/pounding heartbeat, flushing (sudden warmth, redness, or tingly feeling), confusion, headache, dizziness, drowsiness, and thirst. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.
Inform your doctor if you are allergic to Atropine Sulphate Injection 1 ml or any of its ingredients. Before using Atropine Sulphate Injection 1 ml, inform your doctor if you have any medical history, including asthma, glaucoma (elevated pressure in the eye), heart rhythm disorder, liver/kidney diseases, enlarged prostate, stomach diseases or myasthenia gravis (muscle weakness). Atropine Sulphate Injection 1 ml may cause blurred vision, dizziness and drowsiness, hence do not drive or operate machinery until you feel better. Pregnant and breastfeeding women should consult their doctor before using Atropine Sulphate Injection 1 ml. This medicine will be prescribed by a doctor for children depending on the child's age and body weight.
Uses of Atropine Sulphate Injection 1 ml
Bradycardia (slow heart rate), an organophosphate insecticide, nerve gas, and mushroom poisoning, and reduces saliva and mucus secretions in the airway during surgery.
Medicinal Benefits
Atropine Sulphate Injection 1 ml contains Atropine, which is an anticholinergic agent, antisialagogue (that inhibits the flow of saliva), and an antidote. It is used to treat bradycardia (slow heart rate). It also restores a normal heartbeat in cardiac arrest or failure patients. It is used as a preoperative medication before anaesthesia to inhibit salivation and excessive secretions of the respiratory tract. It also acts as an antidote to insecticide, nerve gas, and mushroom poisoning. In combination with other medicines, Atropine Sulphate Injection 1 ml is used to reverse the muscle relaxant effect during surgery.
Directions for Use
It will be administered by a healthcare professional; do not self-administer.
Storage
Store in a cool and dry place away from sunlight
Side Effects of Atropine Sulphate Injection 1 ml

• Constipation

• Bloating

• Stomach pain

• Nausea

• Vomiting

• Dry eyes

• Blurred vision

• Dry mouth

• Fast/pounding heartbeat,

• Flushing (sudden warmth, redness, or tingly feeling)

• Confusion

• Headache

• Dizziness

• Drowsiness

• Thirst

In-Depth Precautions and Warning
Drug Warnings
Before using Atropine Sulphate Injection 1 ml, inform your doctor if you have any medical history, including asthma, glaucoma, heart rhythm disorder, liver/kidney diseases, enlarged prostate, stomach diseases or myasthenia gravis (muscle weakness). Atropine Sulphate Injection 1 ml may cause blurred vision, dizziness and drowsiness, hence do not drive or operate machinery until you feel better. Pregnant and breastfeeding women should consult their doctor before using Atropine Sulphate Injection 1 ml. Alcohol consumption may worsen the side effect of Atropine Sulphate Injection 1 ml like dizziness and drowsiness. It is better to avoid alcohol while you are being treated with Atropine Sulphate Injection 1 ml. This medicine will be prescribed by a doctor for children depending on the child's age and body weight.

Drug Interactions
Drug-Drug Interaction: Atropine Sulphate Injection 1 ml may interact with tricyclic antidepressants, Parkinson’s medication (amantadine), heart-related drugs (mexiletine, disopyramide, quinidine), antifungals (ketoconazole), and antipsychotics (phenothiazine, clozapine),
Drug-Food Interaction: Limit alcohol intake since it may increase the occurrence of side effects like dizziness while being treated with Atropine Sulphate Injection 1 ml.
Drug-Disease Interaction: Atropine Sulphate Injection 1 ml is contraindicated in allergic reactions, urinary difficulties, glaucoma, and stomach-related disorders like achalasia of the oesophagus, a blockage in the intestine (paralytic ileus) or acute form of colonic distension (toxic megacolon).

Drug-Drug Interactions Checker List:
·  AMANTADINE
·  MEXILETINE
·  DISOPYRAMIDE
·  QUINIDINE
·  KETOCONAZOLE
·  PHENOTHIAZINE
·  CLOZAPINE

Safety Advice
ALCOHOL
CAUTION
Alcohol consumption may worsen the side effect of this medicine like dizziness and drowsiness. It is better to avoid alcohol while you are being treated with Atropine Sulphate Injection 1 ml.
 
PREGNANCY
CAUTION
Please inform your doctor if you are pregnant or planning pregnancy. Your doctor will prescribe Atropine Sulphate Injection 1 ml only if the benefits outweigh the risk.
 
BREAST FEEDING
CAUTION
Please inform your doctor if you are breastfeeding. Your doctor will prescribe Atropine Sulphate Injection 1 ml only if the benefits outweigh the risk.
 
DRIVING
CAUTION
Atropine Sulphate Injection 1 ml may cause side effects like dizziness and drowsiness that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.
 
LIVER
CAUTION
Inform your doctor if you have any history of liver diseases or hepatic impairment before receiving Atropine Sulphate Injection 1 ml.
 
KIDNEY
CAUTION
Inform your doctor if you have any history of kidney diseases/impairment before receiving Atropine Sulphate Injection 1 ml.
 
CHILDREN
CAUTION
Please consult your doctor. Your doctor will decide the dose depending on the age and condition of your child.