Celbira 250 Tablet

MANUFACTURER/ MARKETER

Celon Laboratories Ltd

SALT COMPOSITION

Abiraterone Acetate 250mg Tab

STRENGTH

250mg

Storage

Store below 30°C

PRODUCT INTRODUCTION

Celbira Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Celbira Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.  Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.

Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.  You may be asked for regular monitoring of blood glucose level while on treatment.

USES OF CELBIRA TABLET

·         Prostate cancer

BENEFITS OF CELBIRA TABLET

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Celbira Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

SIDE EFFECTS OF CELBIRA TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Celbira

·         Edema (swelling)

·         Vomiting

·         Decreased potassium level in blood

·         Decreased white blood cell count

·         Fatigue

·         Increased liver enzymes

·         Anemia (low number of red blood cells)

·         Urinary tract infection

·         Diarrhea

·         High blood pressure

·         Cough

·         Hypercholesterolemia (high cholesterol)

·         Joint swelling

·         Increased levels of blood fat

·         Altered blood sugar level

HOW TO USE CELBIRA TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Celbira Tablet is to be taken empty stomach.

HOW CELBIRA TABLET WORKS

Celbira Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

SAFETY ADVICE

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Celbira Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Celbira Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

UNSAFE

Celbira Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

SAFE

Celbira Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Celbira Tablet is safe to use in patients with kidney disease. No dose adjustment of Celbira Tablet is recommended.
Because of the limited information, cautious use of Celbira Tablet is recommended in patients with severe kidney disease.

Liver

CAUTION

Celbira Tablet should be used with caution in patients with liver disease. Dose adjustment of Celbira Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.