Inhouse product
PRODUCT
INTRODUCTION
Leukocel 500mg Capsule is used in the
treatment of some kinds of cancer and to prevent painful episodes associated
with sickle cell anemia. It may be also used to treat some other conditions. It
is sometimes used with certain other medicines as part of combination
chemotherapy.
Leukocel 500mg Capsule can be taken with or without food, but try to have it at
the same time every day to get the most benefits. Your doctor will decide what
dose is necessary and how often you need to take it. This will depend on what
you are being treated for and may change from time to time. You should take it
exactly as your doctor has advised. Taking it in the wrong way or taking too
much can cause very serious side effects. It may take several weeks or months
for you to see or feel the benefits but do not stop taking it unless your
doctor tells you to.
The most common side effects of this medicine include hematological disorders,
gastrointestinal symptoms, eating disorders, and weight loss. This medicine may
reduce the number of blood cells in your blood thereby, increasing the
susceptibility to infections. Regular blood tests are required to check your
blood cells along with kidney, liver and heart function during treatment with
this medicine.
Before taking it, tell your doctor if you have bleeding, liver, or kidney
problems or are taking any medicines to treat infections. Many other medicines
can affect, or be affected by, this medicine so let your doctor know all
medications you are using. This medicine is not recommended during pregnancy or
while breastfeeding. The use of effective contraception by both males and
females during treatment is important to avoid pregnancy.
USES OF LEUKOCEL CAPSULE
Head and neck cancer
Sickle cell anemia
Head and neck cancer includes cancer of
the mouth, nose, sinuses or throat. Leukocel 500mg Capsule kills or stops the
growth of cancer cells and also prevents the multiplication of cancer cells. It
is a potent and very toxic medicine and you should discuss the risks and
benefits with your doctor. You should avoid drinking alcohol or smoking while
having this treatment and drink plenty of water to stay hydrated.
Sickle cell anemia is a disorder of the
red blood cells (RBCs) in which they lose their original round shape and
flexibility, turn sickle shape and eventually die out. Leukocel 500mg Capsule
makes your red blood cells bigger. It helps them stay rounder and more flexible
and makes them less likely to turn into a sickle shape. The medicine does this
by increasing a special kind of hemoglobin called hemoglobin F. Hemoglobin F is
also called fetal hemoglobin because newborn babies have it. This helps to
treat this disease and also prevents further complications that may be life-threatening.
Most side effects do not require any medical attention and
disappear as your body adjusts to the medicine. Consult your doctor if they
persist or if you’re worried about them
·
Hematological disorder
·
Gastrointestinal disorder
·
Eating disorder
·
Azoospermia (absence of sperms)
·
Decreased appetite
·
Fever
·
Oligospermia (low sperm count)
·
Skin cancer
·
Bone marrow suppression
·
Hallucination
·
Convulsion
·
Peripheral neuropathy (tingling and numbness of feet and hand)
·
Pulmonary fibrosis
·
Pulmonary edema
·
Pancreatic inflammation
·
Liver toxicity
·
Cutaneous vasculitis
·
Increased uric acid level in blood
Take this medicine in the dose and duration as advised by your
doctor. Leukocel 500mg Capsule may be taken with or without food, but it is
better to take it at a fixed time.
In cancer, Leukocel 500mg Capsule works by blocking an enzyme
(ribonucleotide reductase) which is required for synthesis of DNA. This
prevents the cancer cells from growing and multiplying. In sickle cell disease,
it works by increasing fetal haemoglobin (HbF) levels in red blood cells
(RBCs). This helps the RBCs assume a normal shape, improves blood flow and
protects against complications such as painful sickle cell episodes.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with
Leukocel 500mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Leukocel 500mg Capsule is unsafe to use during pregnancy as
there is definite evidence of risk to the developing baby. However, the doctor
may rarely prescribe it in some life-threatening situations if the benefits are
more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Leukocel 500mg Capsule is probably unsafe to use during
breastfeeding. Limited human data suggests that the drug may pass into the
breastmilk and harm the baby.
Driving
UNSAFE
Leukocel 500mg Capsule may decrease alertness, affect your
vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Leukocel 500mg Capsule should be used with caution in patients
with kidney disease. Dose adjustment of Leukocel 500mg Capsule may be needed.
Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may be advised
while you are taking this medicine.
Liver
CAUTION
Leukocel 500mg Capsule should be used with caution in patients
with liver disease. Dose adjustment of Leukocel 500mg Capsule may be needed.
Please consult your doctor.
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