Luprova 11.25mg Injection
 
MANUFACTURER/ MARKETER
Celon Laboratories Ltd
 
SALT COMPOSITION
Leuprolide Acetate Depot 11.25mg
 
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

PRODUCT INTRODUCTION

Luprova 11.25mg Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty).

Luprova 11.25mg Injection is given as an injection under the skin by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.

Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

USES OF LUPROVA INJECTION

Treatment of Prostate cancer

Treatment of Endometriosis

Treatment of Uterine fibroids

Treatment of Precocious puberty (premature puberty)

BENEFITS OF LUPROVA INJECTION

In Treatment of Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Luprova 11.25mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

In Treatment of Endometriosis

Endometriosis is a condition where tissue like the lining of the womb starts to grow in other places. The main symptoms include pain in your lower stomach or back, period pain, pain during and after sex, constipation, diarrhea and feeling sick. It can also make it difficult to get pregnant. Luprova 11.25mg Injection works by preventing the lining of your womb and any endometriosis tissue from growing too quickly. This will help relieve the symptoms you may have. This medicine needs to be taken regularly to be effective and you may need other medicines or procedures to help control endometriosis.

In Treatment of Uterine fibroids

Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. Luprova 11.25mg Injection helps control the symptoms associated with uterine fibroids such as excessive menstrual bleeding, lower back pain, and also reduces the size of the existing fibroids. It blocks the action of the enzyme responsible for the growth of the broids. As a result, they decrease in size and also stop growing further.

In Treatment of Precocious puberty (premature puberty)

When puberty (change of a child’s body to adult structure and size) begins before age 8 in girls and before age 9 in boys, it is considered precocious puberty. Luprova 11.25mg Injection helps delay this early onset of adulthood and limits the onset of precocious puberty. However, this medicine is given by a doctor and should not be self-administered. Follow your doctor’s instructions carefully for the most benefit.

SIDE EFFECTS OF LUPROVA INJECTION

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Luprova

·         Decreased libido

·         Testicular atrophy

·         Increased sweating

·         Fatigue

·         Muscle weakness

·         Erectile dysfunction

·         Bone pain

·         Injection site reaction

·         Hot flashes

HOW TO USE LUPROVA INJECTION

Your doctor or nurse will give you this medicine. Kindly do not self administer.

HOW LUPROVA INJECTION WORKS

Luprova 11.25mg Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Luprova 11.25mg Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.

SAFETY ADVICE

Alcohol

CAUTION

Caution is advised when consuming alcohol with Luprova 11.25mg Injection. Please consult your doctor.

Pregnancy

UNSAFE

Luprova 11.25mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Luprova 11.25mg Injection during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Luprova 11.25mg Injection may cause side effects which could affect your ability to drive.
Do not drive or operate machinery if you experience drowsiness, dizziness or visual disturbances whilst being treated with Luprova 11.25mg Injection.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Luprova 11.25mg Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Luprova 11.25mg Injection in patients with liver disease. Please consult your doctor.

WHAT IF YOU FORGET TO TAKE LUPROVA INJECTION?

If you miss a dose of Luprova 11.25mg Injection, please consult your doctor.