Magnesium Sulphate 25% Injection 2ml
 
MANUFACTURER/ MARKETER
Vulcan Laboratories Pvt Ltd.
 
SALT COMPOSITION
Magnesium Sulphate Injection USP 25% w/v 2ml

PRODUCT INTRODUCTION

MAGNESIUM SULPHATE 25% contains Magnesium sulphate which belongs to the group of medicines called Fluids and Electrolytes. It is used to treat magnesium deficiency in the body. It can also be used to control and prevent seizure outbreaks (fits) among pregnant women who have severe pre-eclampsia or eclampsia (serious pregnancy complication caused due to abnormally elevated blood pressure).

MAGNESIUM SULPHATE 25% is suitable for use both in adults and in children and can also be used to restore magnesium levels in patients receiving total parenteral nutrition.

Before MAGNESIUM SULPHATE 25% is administered to you, inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have muscle weakness, or low blood calcium levels before receiving MAGNESIUM SULPHATE 25%.

MAGNESIUM SULPHATE 25% may decrease calcium and phosphate levels in the blood. To avoid this, your doctor will constantly monitor the electrolyte levels in your blood and adjust the dose accordingly. It may also cause nausea, vomiting, flushing, headache or drowsiness which usually resolves after few minutes of initiation of the therapy. However, inform your doctor if they worsen.

USES OF MAGNESIUM SULPHATE 25%

• Treats magnesium deficiency
• Prevents and Restores magnesium loss in patients receiving total parenteral nutrition
• Prevents and Controls seizure outbreaks (fits) in pregnant women having pre-eclampsia or eclampsia

HOW MAGNESIUM SULPHATE 25% WORKS

MAGNESIUM SULPHATE 25% is a mineral supplement. It supplements your body with sufficient levels of magnesium which is required to maintain healthy nerves, bones, and muscles. It also regulates heartbeat and provides energy to the body by maintaining blood sugar levels. As a result, it prevents various complications associated with low blood magnesium levels such as nutritional deficiencies, nerve damage and seizure outbreaks.

DIRECTIONS FOR USE

MAGNESIUM SULPHATE 25% will be given to you only by a doctor or a nurse into the vein (as an intravenous infusion) or into the muscles (as an intramuscular injection). Your doctor will decide the correct dose, duration of therapy, and frequency of administration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF MAGNESIUM SULPHATE 25%

COMMON

• Pain and swelling at the site of injection
• Facial flushing, sweating or warmth
• Nausea, vomiting
• Muscle weakness
• Low blood pressure
• Headache, drowsiness
• Irregular or abnormal heartbeat
• Low calcium or phosphate levels in the blood

RARE

Consult your doctor immediately if you experience any of the following side effects after receiving MAGNESIUM SULPHATE 25%:

• Severe allergic reactions (such as skin rashes or itching, swelling of the face, eyelids or lips)

HOW TO MANAGE SIDE EFFECTS

Pain and swelling at the site of injection:

Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor.

Headache:

Try to take rest. Apply a pain-relieving balm on your forehead. If the symptom does not improve, consult with your doctor.

Drowsiness:

Try to rest and relax. Avoid driving or operating heavy tools or machines while you are feeling dizzy. Avoid consumption of alcohol. Consult your doctor if your dizziness did not improve.

WARNING & PRECAUTIONS

PREGNANCY

MAGNESIUM SULPHATE 25% should be used in pregnant women to control fits (caused due to eclampsia or preeclampsia) only if considered necessary by the physician. Your doctor will access the risks and benefits of the therapy and administer the medicine accordingly.

BREASTFEEDING

MAGNESIUM SULPHATE 25% should be used in breastfeeding women only if considered necessary by the physician. Your doctor will access the risks and benefits of the therapy and administer the medicine accordingly.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy or drowsy after receiving MAGNESIUM SULPHATE 25%.

ALCOHOL

Avoid consumption of alcohol while receiving MAGNESIUM SULPHATE 25%.

KIDNEY

MAGNESIUM SULPHATE 25% is not recommended for use in patients with severe kidney diseases, kidney failure or difficulty in urination. It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before receiving it.

LIVER

MAGNESIUM SULPHATE 25% is not recommended for use in patients with severe liver diseases (such as liver failure). It should be used with caution in patients with other liver problems. Therefore, consult your doctor before receiving it.

ALLERGY

Do not receive MAGNESIUM SULPHATE 25% if you are allergic to Magnesium sulphate

HEART DISEASE

MAGNESIUM SULPHATE 25% is not recommended for use in patients with heart problems. Therefore, consult your doctor before receiving it.

OTHERS

MAGNESIUM SULPHATE 25% is not recommended for use if you:

• Have hepatic encephalopathy (loss of brain function due to liver damage)
• Have myasthenia gravies

Before receiving MAGNESIUM SULPHATE 25%, inform your physician if you:

• Have low calcium levels in the blood

·         Use in pediatrics:

·         MAGNESIUM SULPHATE 25% should be used in children and adolescents (aged below 18 years) only if considered necessary by the physician. Therefore, consult your doctor for advice before administration.

·         Use in geriatrics:

·         MAGNESIUM SULPHATE 25% should be used with caution in the elderly patients. Therefore, consult your doctor before receiving it.

INTERACTIONS

Before receiving MAGNESIUM SULPHATE 25%, inform your doctor if you are taking any of the following medicines:

• Medicines used to relax muscles prior to a surgery (such as vecuronium, tubocurarine, suxamethonium)
• Nifedipine or amlodipine (used in the treatment of high blood pressure and chest pain)
• Diuretics (used to reduce edema and blood pressure by increasing urine output) Ex. furosemide, chlorothiazide, hydrochlorothiazide
• Medicines that can reduce anxiety and induce sleep (Ex. diazepam, clonazepam, alprazolam, midazolam, phenobarbital, thiopental)
• Digoxin, digitalis (used to treat heart disease)
• Streptomycin, gentamicin, neomycin (used in the treatment of bacterial infection)
• Morphine or codeine (used in the treatment of bacterial infection)
• Barium (used in the diagnostic test while taking x-ray)

·         Overdosage:

·         MAGNESIUM SULPHATE 25% will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms, contact your doctor immediately.