Ontramab 440mg Injection
 
MANUFACTURER/ MARKETER
Celon Laboratories Ltd
 
SALT COMPOSITION
Trastuzumab 440mg
 
STORAGE
Store in a refrigerator (2 - 8°C). Do not freeze.

PRODUCT INTRODUCTION

Ontramab 440mg Injection is used in the treatment of breast and stomach cancer. It works by killing the cancer cells by inhibiting HER2 (human epidermal growth factor receptor protein).

Ontramab 440mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, headache, rash, insomnia, and infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. You must have to inform your doctor if you experience breathlessness, cough, shivering, swelling of legs and arm.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

USES OF ONTRAMAB INJECTION

Breast cancer

Stomach cancer

BENEFITS OF ONTRAMAB INJECTION

In Breast cancer

Ontramab 440mg Injection is used to treat breast cancer when other medicines have failed to show significant improvement. It helps to stop cancer growth and further spread and relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipple or changes in the shape or texture of the breast. This medicine is given as an injection by a doctor or nurse. Follow your doctor’s instructions carefully to get the most benefit.

In Stomach cancer

Stomach cancer also known as gastric cancer, may occur in the inner lining (called mucosa) of the stomach or in the walls of the stomach. These are of various kinds depending on the origin, affected area and severity of the cancer. Ontramab 440mg Injection helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.

SIDE EFFECTS OF ONTRAMAB INJECTION

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ontramab

·         Anemia (low number of red blood cells)

·         Chills

·         Common cold

·         Cough

·         Decreased blood cells (red cells, white cells, and platelets)

·         Diarrhea

·         Fatigue

·         Fever

·         Headache

·         Heart failure

·         Infection

·         Insomnia (difficulty in sleeping)

·         Mucosal inflammation

·         Nausea

·         Rash

·         Stomatitis (Inflammation of the mouth)

·         Taste change

·         Upper respiratory tract infection

·         Weight loss

HOW TO USE ONTRAMAB INJECTION

Your doctor or nurse will give you this medicine. Kindly do not self administer.

HOW ONTRAMAB INJECTION WORKS

Ontramab 440mg Injection is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.

SAFETY ADVICE

Alcohol

UNSAFE

Ontramab 440mg Injection may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Ontramab 440mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Ontramab 440mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Ontramab 440mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Ontramab 440mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Ontramab 440mg Injection may not be needed in these patients. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Ontramab 440mg Injection in patients with liver disease. Please consult your doctor.

WHAT IF YOU FORGET TO TAKE ONTRAMAB INJECTION?

If you miss a dose of Ontramab 440mg Injection, please consult your doctor.