Stimin 0.5Mg Injection 
 
MANUFACTURER/ MARKETER
Celon Laboratories Ltd
 
SALT COMPOSITION
Neostigmine 0.5mg/ml
 
 
STORAGE
Store in a cool and dry place away from sunlight

About Stimin 0.5 mg Injection 1 ml

Stimin 0.5 mg Injection 1 ml belongs to a group of medicines called 'anticholinesterase agents/acetylcholinesterase inhibitors,' primarily used to treat myasthenia gravis and to reverse the effects of anaesthesia medicines used during surgery. Stimin 0.5 mg Injection 1 ml is also used to treat paralytic ileus (a rare form of constipation) and postoperative urinary retention.

Stimin 0.5 mg Injection 1 ml contains 'Neostigmine.' It increases levels of a neurotransmitter called acetylcholine by stopping the excess cholinesterase activity (an enzyme required to break down acetylcholine) involved in communication between nerve impulses and muscle movements. Neurotransmitters are chemical messengers that transmit the message from one nerve cell to another nerve cell, muscle cell, or gland cell. Thus Stimin 0.5 mg Injection 1 ml helps in proper muscle functioning and prevents muscle weakness.

Stimin 0.5 mg Injection 1 ml will be administered by a health care professional, do not self-administer. Your dose and duration will be based on the severity of your medical condition. In some cases, you may experience common side effects, such as nausea, vomiting, slow heartbeat, abdominal cramp, diarrhoea, increased saliva production, dizziness, headache, trouble sleeping, and dry mouth. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor before using this medicine if you have a history of liver, heart or kidney diseases, asthma, stomach ulcer, fits, Parkinson's disease, overactive thyroid, or vagotonia/irritability of the vagus nerve (connects to the abdomen from the brain) that causes excess bowel contractions. Let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before starting Stimin 0.5 mg Injection 1 ml. Avoid consuming alcohol during the course to prevent unwanted side effects. Stimin 0.5 mg Injection 1 ml can be given to children if prescribed by the doctor; the dose depends on the child's age and weight.

Uses of Stimin 0.5 mg Injection 1 ml

Myasthenia gravis, paralytic ileus, and post-operative urinary retention.

Medicinal Benefits

Stimin 0.5 mg Injection 1 ml belongs to the group of medicines called 'anticholinesterase agents/cholinesterase inhibitors and is used to treat myasthenia gravis (muscle weakness). Stimin 0.5 mg Injection 1 ml contains 'Neostigmine'. It stops the excessive activity of cholinesterase, helping the muscles work properly. Additionally, Stimin 0.5 mg Injection 1 ml is used to treat paralytic ileus (a rare form of constipation) and postoperative urinary retention. It reverses the effects of neuromuscular blocking agents/anaesthesia medicines used during surgery. Stimin 0.5 mg Injection 1 ml affects the chemicals in the body, which are involved in communication between nerve impulses and muscle movements. Thereby, Stimin 0.5 mg Injection 1 ml treats muscle-associated disorders by improving muscle strength.

Directions for Use

A healthcare professional will administer it; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Stimin 0.5 mg Injection 1 ml

• Nausea
• Vomiting
• Slow heartbeat
• Abdominal cramp
• Diarrhoea
• Increased saliva production
• Dizziness
• Headache
• Trouble sleeping
• Dry mouth

In-Depth Precautions and Warning

Drug Warnings

Let your doctor know if you use any other medicines or supplements before using Stimin 0.5 mg Injection 1 ml. Brief your medical history if you have any liver or kidney diseases, heart diseases (coronary artery disease, irregular heartbeat), asthma, stomach ulcer, fits, urination problems, Parkinson's disease, overactive thyroid, and vagotonia before starting Stimin 0.5 mg Injection 1 ml. Please consult your doctor if you are pregnant, planning to conceive or are a breastfeeding mother. Avoid consuming alcohol to get the maximum benefits of the medicine and prevent the disease's aggravation. Drive or operate machinery only when you are alert and focused during the course.

Drug Interactions

Drug-Drug Interaction: Stimin 0.5 mg Injection 1 ml may interact with anaesthetics (halothane, cyclopropane), muscle relaxants (succinylcholine, suxamethonium), and antibiotics (neomycin, streptomycin).

Drug-Food Interaction: Avoid alcohol intake while being treated with Stimin 0.5 mg Injection 1 ml.

Drug-Disease Interaction: Let your doctor know if you have asthma, bradycardia (slow heart rate), bronchospasm, fits, overactive thyroid, stomach ulcer, coronary artery disease, urination problems, Parkinson's disease, or irritability of vagus nerve before starting Stimin 0.5 mg Injection 1 ml.

Drug-Drug Interactions Checker List:

·  HALOTHANE

·  CYCLOPROPANE

·  SUCCINYLCHOLINE

·  SUXAMETHONIUM

·  NEOMYCIN

·  STREPTOMYCIN

Safety Advice

·         

ALCOHOL

CAUTION

Avoid consuming alcohol during the course with Stimin 0.5 mg Injection 1 ml to prevent any undesirable side effects.

·         

PREGNANCY

CAUTION

There is limited information on how Stimin 0.5 mg Injection 1 ml affects pregnancy. If you are pregnant or planning to conceive, inform your doctor before taking Stimin 0.5 mg Injection 1 ml.

·        

BREAST FEEDING

CAUTION

It is not known if Neostigmine is excreted into breast milk. Please inform your doctor before taking Stimin 0.5 mg Injection 1 ml if you are a breastfeeding mother.

·    

DRIVING

CAUTION

Neostigmine may make you feel dizzy and affect your ability to drive. It is advised not to drive or operate machinery while being treated with Stimin 0.5 mg Injection 1 ml if you are not mentally alert and focused.

·        

LIVER

CAUTION

Please inform your doctor before receiving Stimin 0.5 mg Injection 1 ml if you have liver problems.

KIDNEY

CAUTION

Please inform your doctor before receiving Stimin 0.5 mg Injection 1 ml if you have kidney disease.

CHILDREN

CAUTION

Stimin 0.5 mg Injection 1 ml is recommended in children below 12 years of age only when prescribed by the doctor. The dosage depends on the child's age, weight and condition.

Habit Forming

No

Diet & Lifestyle Advise

• Maintain proper weight by following a healthy diet.
• Avoid smoking and alcohol consumption.
• Try to avoid stress by practising meditation or yoga.
• Include fruits and vegetables in your diet as they contain antioxidants.
• Eat warm meals rather than hot meals, as heat aggravates the disease.
• Try sipping a cold drink while having hot or warm meals.
• Avoid foods that require a lot of chewing, like tough meats.
• Exercise regularly to keep your muscles strong
• Limit foods with high cholesterol and saturated fats.
• Cut down on sugar, salt and processed foods.
• Drink plenty of water.

Special Advise

Stimin 0.5 mg Injection 1 ml might interfere with the effects of skeletal muscle relaxants used in the surgery.